Hyaluronic acid levels can predict risk of serious liver events in people living with HIV and hepatitis B or C co-infection

A simple blood test can predict the risk of liver-related death or hepatic encephalopathy for people living with HIV who have hepatitis B or hepatitis C co-infection, investigators from the EuroSIDA cohort report in PLoS One.

Their results showed that baseline elevations in plasma levels of hyaluronic acid (HA) were associated with a significant increase in the risk of serious liver-related events. Levels of this biomarker remained stable in people who remained 'event free', but increased in those experiencing disease progression.

“The present study indicates that HA could be a useful biomarker to estimate the long-term risk of liver disease,” write the authors.

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