Monday, October 7, 2013

HBV Vaccine Response Status Not Associated with cART CD4 Gains at 1-Year

Hepatitis B virus (HBV) vaccine response status was not associated with post-combination antiretroviral therapy (cART) CD4 gains at 1-year among those with virologic suppression, a study concluded at IDWeek 2013.

Noting that HBV vaccine antibody response has been associated with reduced risk of AIDS or death but that the association between HBV vaccine response status and cART outcomes has not been well studied, Kahtonna Allen, DO, MS, from the Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, MD, and the Infectious Disease Service, San Antonio Military Medical Center, Fort Sam Houston, TX, and colleagues evaluated CD4 gains post-cART according to HBV vaccine antibody response in the US Military HIV Natural History Study.

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