Hepatitis B virus (HBV) vaccine response status was not associated with post-combination antiretroviral therapy (cART) CD4 gains at 1-year among those with virologic suppression, a study concluded at IDWeek 2013.
Noting that HBV vaccine antibody response has been associated with
reduced risk of AIDS or death but that the association between HBV
vaccine response status and cART outcomes has not been well studied,
Kahtonna Allen, DO, MS, from the Infectious Disease Clinical Research
Program, Uniformed Services University of the Health Sciences, Bethesda,
MD, and the Infectious Disease Service, San Antonio Military Medical
Center, Fort Sam Houston, TX, and colleagues evaluated CD4 gains
post-cART according to HBV vaccine antibody response in the US Military
HIV Natural History Study.