Thursday, October 3, 2013

Liver transplant outcomes among HBV patients improved over time

Liver transplant outcomes among HBV patients improved over time

Outcomes from liver transplantation due to hepatitis B infection improved with the emergence of new therapies, though the effect was less pronounced among women and African-Americans in a recent study.
Researchers performed a retrospective chart review to determine outcomes among 738 patients who received orthotopic liver transplantation (OLT) due to hepatitis B infection between 1985 and 1994 (era 1), 1995 and 2004 (era 2) and 2005 and 2010 (era 3). Hepatitis B immunoglobulin (HBIG) was the most prominent treatment method used during era 1, HBIG with lamivudine (LAM) during era 2 and HBIG in combination with antiviral therapy during era 3.

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