AASLD 2013: Long-Term Trials Show Tenofovir Effective



— Christine M. Kukka, Project Manager, HBV Advocate

In two trials, tenofovir was shown to be safe and effective over a seven-year treatment period with no signs of drug resistance despite long-term treatment. Studies also showed a relatively low rate of kidney damage or bone loss.

In one study, 154 patients were treated long-term had the following results:
Control ID 1735577. Seven years of treatment with tenofovir DF for chronic hepatitis B virus infection is safe and well tolerated and associated with sustained virological, biochemical and serological responses with no detectable resistance. (Abstract #926)

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