Lamivudine a poor choice for lowering viral load in pregnant women:
Twenty-one women with high viral load were treated with
lamivudine for about 53 days toward the end of their pregnancies.
None transmitted the infection to their newborns, but they had only
modest reductions in viral load and four women developed some form
of drug resistance.
Control ID 1735799. Short duration of
lamivudine for prevention of HBV transmission in pregnancy: Lack
of potency and selection of resistance mutations. (Abstract #1018)