— Christine M. Kukka, Project Manager, HBV Advocate
Does antiviral treatment over an entire pregnancy
harm the infant? Researchers followed infants born to 200 women
treated with the antiviral telbivudine (Tyzeka) for most of their
pregnancies for up to four years to see what impact the antiviral
treatment had on the children's development. None of the 202 infants
were infected with HBV and all developed normally, without any birth
defects or abnormalities. (1)
Infants born to 14 women treated
with tenofovir over the entire course of their pregnancy were all
healthy without any side effects from their mothers' antiviral
treatment. None became HBV-infected and there were no safety issues
reported, even among women who breastfed their babies while taking
tenofovir. (2)
1. Control ID: 1736328.
Long-term safety and efficacy of infants born to telbivudine treated
highly viremic mothers with HBeAg positive chronic hepatitis B (CHB)
during 2nd or 3rd trimester. (Abstract #935)
2. Control ID 1737088. Efficacy and safety
results of tenofovir DF (TDF) treatment from the first trimester in HBV
pregnant women in real-life clinical practice. (Abstract #952)
Labels: antivirals when pregnant