Wednesday, March 26, 2014

HIV, hepatitis B virus coinfection increased hepatitis D incidence

The prevalence of recent hepatitis D virus infection among patients with HIV/hepatitis B virus coinfection has increased significantly since 1992, according to recent study findings.

Additionally, recent hepatitis D virus (HDV) seroconversion was found to be associated with hepatitis flares and syphilis.

In the retrospective cohort study, researchers evaluated 375 patients coinfected with HIV and hepatitis B virus (HBV) who were seen at the National Taiwan University Hospital between 1992 and 2012. Blood samples were taken to detect the presence of anti-HDV immunoglobulin G to establish the approximate HDV incidence between 1992 and 2012. In addition, the investigators determined the plasma HDV and HBV viral loads and HBV surface antigen (HBsAg) concentrations for the HDV seroconverters.



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