Global hepatitis B epidemic treatable at cost of just $36 per patient per year

Large-scale production of generic entecavir could cut the cost of first-line hepatitis B virus (HBV) therapy to just US$36 per patient per year, according to a study published in the online version of the Journal of Virus Eradication. The authors believe that this cost could facilitate low-cost global therapy for HBV. The cost of scaled-up generic production of entecavir was shown to be significantly cheaper than that associated with alternative therapies, including tenofovir.

“Hepatitis B infection leads to approximately 686,000 deaths per year. This life-threatening viral infection could be controlled using entecavir treatment costing $36/person-year,” comment the investigators. “Entecavir priced at $36/patient-year could allow expansion of chronic hepatitis B treatment in low- and middle-income countries, avoiding significant numbers of cases of cirrhosis and/or primary liver cancer, and massive savings in high-income countries.”

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