Intradermal HBV vaccine safe, effective for intramuscular nonresponders

HealthDay News -- For intramuscular hepatitis B virus vaccine nonresponders, intradermal vaccine administration seems efficacious and safe, according to a study published in the Journal of Gastroenterology and Hepatology.

About 5% to 10% of people fail to develop a protective immune response to hepatitis B virus (HBV) vaccination, which has important implications for health care workers, families living in households with people that have HBV, and others who may be at increased risk of exposure to HBV.


So Or Kalchiem-Dekel, MD, from the Soroka University Medical Center in Israel, and colleagues designed a prospective case series to examine efficacy, safety, and durability of intradermal vaccine administration in those who have not responded well to intramuscular HBV vaccine.

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