Effective vaccination for persons that do not respond to standard Hepatitis B vaccines
Maastricht, The Netherlands, 03 November 2015 – CyTuVax, a life science company focusing on the development of cancer, viral and bacterial vaccines, today announced the start of a phase I clinical trial assessing the safety and efficacy of its lead product, a Hepatitis B HBAI20 vaccine for non-responders to standard Hepatitis B vaccines. This trial will be conducted at the Ease Travel Clinic by the Department of Medical Microbiology of the MAASTRICHT UMC and is coordinated by Dr. A.M. L. Oude Lashof, MD PhD, Internist and Consultant Infectious Diseases of Maastricht UMC. The trial, for which 36 subjects are being recruited, will start in the course of October 2015 and data are expected to be published in Q3 of 2016.
Hepatitis B is an infectious disease caused by the hepatitis B virus (HBV), and could lead to acute or chronic liver inflammation that might trigger liver failure and liver cancer. Many people have no symptoms during the initial infection. Worldwide an estimated 360 million people are chronically infected, of whom almost one million people die annually of HBV-related liver disease. Chronic hepatitis B is the major cause of hepatocellular carcinoma (HCC), the most common type of liver cancer. The disease occurs in particular in Africa, south of the Sahara and in East Asia, where around 10% of the adults are chronic carriers of the virus.
Read more....Labels: boosters, HBV vaccine, vaccine phase 1